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Multiplexed monitoring of therapeutic antibodies for inflammatory diseases using Fab-selective proteolysis nSMOL coupled with LC-MS.
Iwamoto, Noriko; Takanashi, Megumi; Yokoyama, Kotoko; Yonezawa, Atsushi; Denda, Masaya; Hashimoto, Motomu; Tanaka, Masao; Ito, Hiromu; Matsuura, Minoru; Yamamoto, Shuji; Honzawa, Yusuke; Matsubara, Kazuo; Shimada, Takashi.
Afiliação
  • Iwamoto N; Shimadzu Bioscience Research Partnership, Shimadzu Scientific Instruments, 21720 23rd Drive Southeast #250, Bothell, Washington 98021, USA; Leading Technology of Bioanalysis and Protein Chemistry, Shimadzu Corporation, Med-Pharm Collaboration Building of Kyoto University, 46-29 Yoshida-Shimo-Adachi-
  • Takanashi M; Leading Technology of Bioanalysis and Protein Chemistry, Shimadzu Corporation, Med-Pharm Collaboration Building of Kyoto University, 46-29 Yoshida-Shimo-Adachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.
  • Yokoyama K; Leading Technology of Bioanalysis and Protein Chemistry, Shimadzu Corporation, Med-Pharm Collaboration Building of Kyoto University, 46-29 Yoshida-Shimo-Adachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.
  • Yonezawa A; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan; Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimo-Adachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.
  • Denda M; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan; Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimo-Adachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.
  • Hashimoto M; Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
  • Tanaka M; Department of Advanced Medicine for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
  • Ito H; Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
  • Matsuura M; Department of Gastroenterology & Hepatology, Graduate School of Medicine, Kyoto University, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
  • Yamamoto S; Department of Gastroenterology & Hepatology, Graduate School of Medicine, Kyoto University, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
  • Honzawa Y; Department of Gastroenterology & Hepatology, Graduate School of Medicine, Kyoto University, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
  • Matsubara K; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
  • Shimada T; Shimadzu Bioscience Research Partnership, Shimadzu Scientific Instruments, 21720 23rd Drive Southeast #250, Bothell, Washington 98021, USA; Leading Technology of Bioanalysis and Protein Chemistry, Shimadzu Corporation, Med-Pharm Collaboration Building of Kyoto University, 46-29 Yoshida-Shimo-Adachi-
J Immunol Methods ; 472: 44-54, 2019 09.
Article em En | MEDLINE | ID: mdl-31201793
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatografia Líquida / Espectrometria de Massas em Tandem / Inflamação / Anticorpos Monoclonais Tipo de estudo: Observational_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatografia Líquida / Espectrometria de Massas em Tandem / Inflamação / Anticorpos Monoclonais Tipo de estudo: Observational_studies Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article