FAM3A protects chondrocytes against interleukin-1ß-induced apoptosis through regulating PI3K/Akt/mTOR pathway.

Yan, Song; Jiang, Changqing; Li, Hong; Li, Deyan; Dong, Wei

Yan, Song; Jiang, Changqing; Li, Hong; Li, Deyan; Dong, Wei.

Afiliação

Yan S; Bone and Joint Surgery, Shenzhen Baoan Shiyan People's Hospital, China.
Jiang C; Department of Sports Medicine, Peking University Shenzhen Hospital, China.
Li H; Department of General Surgery, People's Hospital of Baoan District, China.
Li D; Bone and Joint Surgery, Shenzhen Baoan Shiyan People's Hospital, China.
Dong W; Bone and Joint Surgery, Shenzhen Baoan Shiyan People's Hospital, China. Electronic address: dwbonejs@163.com.

Biochem Biophys Res Commun ; 516(1): 209-214, 2019 08 13.

Article em En | MEDLINE | ID: mdl-31208715

Assuntos

Condrócitos/patologia; Citocinas/imunologia; Interleucina-1beta/imunologia; Osteoartrite/imunologia; Animais; Apoptose; Condrócitos/imunologia; Camundongos; Camundongos Endogâmicos C57BL; Osteoartrite/patologia; Fosfatidilinositol 3-Quinases/imunologia; Proteínas Proto-Oncogênicas c-akt/imunologia; Transdução de Sinais; Serina-Treonina Quinases TOR/imunologia

Palavras-chave

Apoptosis; Chondrocyte; FAM3A; Interleukin-1ß; Osteoarthritis; PI3K/Akt/mTOR pathway

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Citocinas / Condrócitos / Interleucina-1beta Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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