A note on the empirical Bayes heterogeneity variance estimator in meta-analysis.
Stat Med
; 38(20): 3804-3816, 2019 09 10.
Article
em En
| MEDLINE
| ID: mdl-31209917
ABSTRACT
This paper focuses on the empirical Bayes (EB) or Mandel-Paule estimator of the heterogeneity variance in meta-analysis, which was discussed by Morris and proposed in earlier publications by Mandel and Paule in an inter-laboratory context. The relationship of the EB estimator to other heterogeneity variance estimators typically used in meta-analysis is explored, and approximate variance estimators for the EB estimate of the heterogeneity variance are proposed based on the M-estimation method. Statistical inference for the overall treatment effect using the EB estimator and the proposed standard errors is discussed using two example data sets from meta-analysis applications.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Metanálise como Assunto
/
Teorema de Bayes
Tipo de estudo:
Prognostic_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article