DNA sequence analysis of X-ray-induced deletions at the white locus of Drosophila melanogaster.
Mutat Res
; 207(1): 23-8, 1988 Jan.
Article
em En
| MEDLINE
| ID: mdl-3122035
ABSTRACT
We have determined the nucleotide sequence of 5 X-ray-induced white mutants containing small rearrangements. Comparison with wild-type sequences showed deletions in the coding region ranging in size between 6 bp and 29 bp. These small deletions are distributed non-randomly over the white locus. Two mutants contain the same 29-bp deletion, while the other 3 deletions are clustered. All 5 deletions have occurred between 2 and 3 bp repeats. One of the repeats is preserved in the novel junction formed by the deletion. Our results suggest that recombinational processes may be involved in the generation of X-ray-induced deletions.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Recombinação Genética
/
Deleção Cromossômica
/
Drosophila melanogaster
/
Mutação
Limite:
Animals
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article