Relationship between structural damage with loss of strength and functional disability in psoriatic arthritis patients.
Clin Biomech (Bristol, Avon)
; 68: 169-174, 2019 08.
Article
em En
| MEDLINE
| ID: mdl-31220740
ABSTRACT
BACKGROUND:
Evaluate the relationship between structural damage assessed by radiography or ultrasonography in the hands of patients with psoriatic arthritis (PsA) with loss of strength together with functional disability.METHODS:
A cross-sectional study was conducted in patients with PsA involving the hands. Erosions and loss of radiographic joint space were measured in the dominant hand using a modified Sharp van der Heijde method and an ultrasound assessment. Hand strength was assessed with a dynamometer and disability was assessed using the Health Assessment Questionnaire (HAQ). The statistical analysis was performed using multiple linear regression models.FINDINGS:
76 patients were included with a mean age of 57⯱â¯9.9â¯years, with 56.6% women. A statistically significant relationship was found between presence of erosions and reduction in lateral (pâ¯=â¯0.027) and tip (pâ¯=â¯0.030) pinch strength in the hand. This was also the case for loss of joint space and reduction in lateral (pâ¯=â¯0.012) and tip (pâ¯=â¯0.006) pinch strength. There was an association between total ultrasound (US) alterations and reduction in lateral pinch strength (pâ¯=â¯0.03). An association was also observed between erosions, loss of joint space and total US alterations and disability measured by the HAQ (pâ¯<â¯0.001; <0.001; 0.012, respectively). HAQ scores were associated with a decrease in mean lateral (pâ¯<â¯0.001) and tip (pâ¯<â¯0.001) pinch strength.INTERPRETATION:
In patients with PsA involving the hands, structural alterations of the dominant hand assessed by conventional x-ray and ultrasound are associated with loss of strength measured objectively with dynamometry and greater disability also studied subjectively using the HAQ.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Artrite Reumatoide
/
Artrite Psoriásica
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Força da Mão
/
Mãos
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article