Development and characterization of a theranostic multimodal anti-PSMA targeting agent for imaging, surgical guidance, and targeted photodynamic therapy of PSMA-expressing tumors.

Lütje, Susanne; Heskamp, Sandra; Franssen, Gerben M; Frielink, Cathelijne; Kip, Annemarie; Hekman, Marlène; Fracasso, Giulio; Colombatti, Marco; Herrmann, Ken; Boerman, Otto C; Gotthardt, Martin; Rijpkema, Mark

Lütje, Susanne; Heskamp, Sandra; Franssen, Gerben M; Frielink, Cathelijne; Kip, Annemarie; Hekman, Marlène; Fracasso, Giulio; Colombatti, Marco; Herrmann, Ken; Boerman, Otto C; Gotthardt, Martin; Rijpkema, Mark.

Afiliação

Lütje S; Department of Radiology and Nuclear Medicine, Radboud university medical center, Nijmegen, the Netherlands.
Heskamp S; Clinic for Nuclear Medicine, University Hospital Essen, Germany.
Franssen GM; Department of Nuclear Medicine, University Hospital Bonn, Bonn, Germany.
Frielink C; Department of Radiology and Nuclear Medicine, Radboud university medical center, Nijmegen, the Netherlands.
Kip A; Department of Radiology and Nuclear Medicine, Radboud university medical center, Nijmegen, the Netherlands.
Hekman M; Department of Radiology and Nuclear Medicine, Radboud university medical center, Nijmegen, the Netherlands.
Fracasso G; Department of Radiology and Nuclear Medicine, Radboud university medical center, Nijmegen, the Netherlands.
Colombatti M; Department of Radiology and Nuclear Medicine, Radboud university medical center, Nijmegen, the Netherlands.
Herrmann K; Department of Medicine, University of Verona, Verona, Italy.
Boerman OC; Department of Medicine, University of Verona, Verona, Italy.
Gotthardt M; Clinic for Nuclear Medicine, University Hospital Essen, Germany.
Rijpkema M; Department of Radiology and Nuclear Medicine, Radboud university medical center, Nijmegen, the Netherlands.

Theranostics ; 9(10): 2924-2938, 2019.

Article em En | MEDLINE | ID: mdl-31244933

Assuntos

Antígenos de Superfície/análise; Glutamato Carboxipeptidase II/análise; Neoplasias da Próstata/diagnóstico; Neoplasias da Próstata/tratamento farmacológico; Coloração e Rotulagem/métodos; Nanomedicina Teranóstica/métodos; Animais; Modelos Animais de Doenças; Xenoenxertos; Masculino; Camundongos Endogâmicos BALB C; Camundongos Nus; Terapia de Alvo Molecular/métodos; Transplante de Neoplasias; Imagem Óptica/métodos; Fotoquimioterapia/métodos; Cirurgia Assistida por Computador/métodos

Palavras-chave

PSMA; intra-operative; near-infrared fluorescence; prostate cancer; targeted photodynamic therapy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Coloração e Rotulagem / Glutamato Carboxipeptidase II / Nanomedicina Teranóstica / Antígenos de Superfície Tipo de estudo: Guideline / Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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