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Inadequate DNA Damage Repair Promotes Mammary Transdifferentiation, Leading to BRCA1 Breast Cancer.
Wang, Hua; Xiang, Dongxi; Liu, Ben; He, Aina; Randle, Helena J; Zhang, Kelvin Xi; Dongre, Anushka; Sachs, Norman; Clark, Allison P; Tao, Luwei; Chen, Qing; Botchkarev, Vladimir V; Xie, Ying; Dai, Ning; Clevers, Hans; Li, Zhe; Livingston, David M.
Afiliação
  • Wang H; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Departments of Genetics and Medicine, Harvard Medical School, Boston, MA 02115, USA.
  • Xiang D; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Liu B; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Departments of Genetics and Medicine, Harvard Medical School, Boston, MA 02115, USA.
  • He A; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Randle HJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Departments of Genetics and Medicine, Harvard Medical School, Boston, MA 02115, USA.
  • Zhang KX; Informatics IT, Merck & Co., Boston, MA 02115, USA.
  • Dongre A; Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA.
  • Sachs N; Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands.
  • Clark AP; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Departments of Genetics and Medicine, Harvard Medical School, Boston, MA 02115, USA.
  • Tao L; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Chen Q; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Botchkarev VV; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Departments of Genetics and Medicine, Harvard Medical School, Boston, MA 02115, USA.
  • Xie Y; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Dai N; Department of Medicine, Robert Wood Johnson Medical School, Rutgers, New Brunswick, NJ 08901, USA.
  • Clevers H; Hubrecht Institute, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands.
  • Li Z; Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. Electronic address: zli4@rics.bwh.harvard.edu.
  • Livingston DM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Departments of Genetics and Medicine, Harvard Medical School, Boston, MA 02115, USA. Electronic address: david_livingston@dfci.harvard.edu.
Cell ; 178(1): 135-151.e19, 2019 06 27.
Article em En | MEDLINE | ID: mdl-31251913
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Neoplasias da Mama / Proteína BRCA1 / Reparo do DNA / Transdiferenciação Celular / Glândulas Mamárias Animais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dano ao DNA / Neoplasias da Mama / Proteína BRCA1 / Reparo do DNA / Transdiferenciação Celular / Glândulas Mamárias Animais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article