Identification, functional and structural characterization of novel aminoglycoside phosphotransferase APH(3â³)-Id from Streptomyces rimosus subsp. rimosus ATCC 10970.

Alekseeva, Maria G; Boyko, Konstantin M; Nikolaeva, Alena Yu; Mavletova, Dilara A; Rudakova, Natalia N; Zakharevich, Natalia V; Korzhenevskiy, Dmitry A; Ziganshin, Rustam H; Popov, Vladimir O; Danilenko, Valery N

Identification, functional and structural characterization of novel aminoglycoside phosphotransferase APH(3â³)-Id from Streptomyces rimosus subsp. rimosus ATCC 10970.

Alekseeva, Maria G; Boyko, Konstantin M; Nikolaeva, Alena Yu; Mavletova, Dilara A; Rudakova, Natalia N; Zakharevich, Natalia V; Korzhenevskiy, Dmitry A; Ziganshin, Rustam H; Popov, Vladimir O; Danilenko, Valery N.

Afiliação

Alekseeva MG; Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia. Electronic address: Alekseevamg@mail.ru.
Boyko KM; Bach Institute of Biochemistry, Federal Research Centre of Biotechnology of the Russian Academy of Sciences, Moscow, 119071, Russia. Electronic address: kmb@inbi.ras.ru.
Nikolaeva AY; National Research Center "Kurchatov Institute", Moscow, 123182, Russia.
Mavletova DA; Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia.
Rudakova NN; Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia.
Zakharevich NV; Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia.
Korzhenevskiy DA; National Research Center "Kurchatov Institute", Moscow, 123182, Russia.
Ziganshin RH; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russia.
Popov VO; Bach Institute of Biochemistry, Federal Research Centre of Biotechnology of the Russian Academy of Sciences, Moscow, 119071, Russia; National Research Center "Kurchatov Institute", Moscow, 123182, Russia.
Danilenko VN; Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia.

Arch Biochem Biophys ; 671: 111-122, 2019 08 15.

Article em En | MEDLINE | ID: mdl-31251922

Assuntos

Proteínas de Bactérias/química; Fosfotransferases (Aceptor do Grupo Álcool)/química; Streptomyces rimosus/enzimologia; Sequência de Aminoácidos; Antibacterianos/farmacologia; Proteínas de Bactérias/genética; Proteínas de Bactérias/isolamento & purificação; Biologia Computacional; Escherichia coli/efeitos dos fármacos; Escherichia coli/genética; Genes Bacterianos; Fosforilação; Fosfotransferases (Aceptor do Grupo Álcool)/genética; Fosfotransferases (Aceptor do Grupo Álcool)/isolamento & purificação; Filogenia; Processamento de Proteína Pós-Traducional; Estrutura Terciária de Proteína; Proteínas Recombinantes/química; Proteínas Recombinantes/genética; Proteínas Recombinantes/isolamento & purificação; Alinhamento de Sequência; Estreptomicina/farmacologia

Palavras-chave

3D structure; APH(3â³)-Id; Aminoglycoside phosphotransferase; Antibiotic resistance; Streptomyces rimosus; Streptomycin phosphotransferase; X-ray

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Fosfotransferases (Aceptor do Grupo Álcool) / Streptomyces rimosus Tipo de estudo: Diagnostic_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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