PIK3CA hotspot mutations in circulating tumor cells and paired circulating tumor DNA in breast cancer: a direct comparison study.

Tzanikou, Eleni; Markou, Athina; Politaki, Eleni; Koutsopoulos, Anastasios; Psyrri, Amanda; Mavroudis, Dimitris; Georgoulias, Vassilis; Lianidou, Evi

Tzanikou, Eleni; Markou, Athina; Politaki, Eleni; Koutsopoulos, Anastasios; Psyrri, Amanda; Mavroudis, Dimitris; Georgoulias, Vassilis; Lianidou, Evi.

Afiliação

Tzanikou E; Analysis of Circulating Tumor Cells, Lab of Analytical Chemistry, Department of Chemistry, University of Athens, Greece.
Markou A; Analysis of Circulating Tumor Cells, Lab of Analytical Chemistry, Department of Chemistry, University of Athens, Greece.
Politaki E; Laboratory of Translational Oncology, Medical School, University of Crete, Heraklion, Greece.
Koutsopoulos A; Laboratory of Translational Oncology, Medical School, University of Crete, Heraklion, Greece.
Psyrri A; Oncology Unit, 2nd Department of Internal Medicine-Propaedeutic, Attikon University Hospital, Haidari, Greece.
Mavroudis D; Laboratory of Translational Oncology, Medical School, University of Crete, Heraklion, Greece.
Georgoulias V; METROPOLITAN General Hospital, Athens, Greece.
Lianidou E; Analysis of Circulating Tumor Cells, Lab of Analytical Chemistry, Department of Chemistry, University of Athens, Greece.

Mol Oncol ; 13(12): 2515-2530, 2019 12.

Article em En | MEDLINE | ID: mdl-31254443

Assuntos

Neoplasias da Mama; DNA Tumoral Circulante; Classe I de Fosfatidilinositol 3-Quinases; Mutação de Sentido Incorreto; Células Neoplásicas Circulantes; Substituição de Aminoácidos; Neoplasias da Mama/sangue; Neoplasias da Mama/genética; Neoplasias da Mama/patologia; DNA Tumoral Circulante/sangue; DNA Tumoral Circulante/genética; Classe I de Fosfatidilinositol 3-Quinases/sangue; Classe I de Fosfatidilinositol 3-Quinases/genética; Feminino; Humanos; Células MCF-7; Células Neoplásicas Circulantes/metabolismo; Células Neoplásicas Circulantes/patologia

Palavras-chave

PIK3CA; breast cancer; circulating tumor DNA; circulating tumor cells; liquid biopsy; mutation analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Mutação de Sentido Incorreto / Classe I de Fosfatidilinositol 3-Quinases / DNA Tumoral Circulante / Células Neoplásicas Circulantes Limite: Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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