Evidence for the induction of Th2 inflammation by group 2 innate lymphoid cells in response to prostaglandin D<sub>2</sub> and cysteinyl leukotrienes in allergic rhinitis.

Tojima, Ichiro; Matsumoto, Koji; Kikuoka, Hirotaka; Hara, Shiori; Yamamoto, Sayuri; Shimizu, Shino; Kouzaki, Hideaki; Shimizu, Takeshi

Evidence for the induction of Th2 inflammation by group 2 innate lymphoid cells in response to prostaglandin D₂ and cysteinyl leukotrienes in allergic rhinitis.

Tojima, Ichiro; Matsumoto, Koji; Kikuoka, Hirotaka; Hara, Shiori; Yamamoto, Sayuri; Shimizu, Shino; Kouzaki, Hideaki; Shimizu, Takeshi.

Afiliação

Tojima I; Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan.
Matsumoto K; Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan.
Kikuoka H; Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan.
Hara S; Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan.
Yamamoto S; Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan.
Shimizu S; Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan.
Kouzaki H; Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan.
Shimizu T; Department of Otorhinolaryngology, Shiga University of Medical Science, Otsu, Japan.

Allergy ; 74(12): 2417-2426, 2019 12.

Article em En | MEDLINE | ID: mdl-31267527

Assuntos

Cisteína/metabolismo; Imunidade Inata; Leucotrienos/metabolismo; Prostaglandina D2/metabolismo; Rinite Alérgica/etiologia; Rinite Alérgica/metabolismo; Células Th2/imunologia; Células Th2/metabolismo; Alérgenos/imunologia; Animais; Biomarcadores; Estudos de Casos e Controles; Citocinas/metabolismo; Suscetibilidade a Doenças; Feminino; Humanos; Imunofenotipagem; Contagem de Linfócitos; Masculino; Mucosa/imunologia; Mucosa/metabolismo; Líquido da Lavagem Nasal/imunologia; Pyroglyphidae/imunologia

Palavras-chave

allergic rhinitis; cysteinyl leukotriene; eosinophil; group 2 innate lymphoid cells; prostaglandin D2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prostaglandina D2 / Leucotrienos / Células Th2 / Cisteína / Rinite Alérgica / Imunidade Inata Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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