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The tyrosine kinase inhibitor dasatinib acts as a pharmacologic on/off switch for CAR T cells.
Mestermann, Katrin; Giavridis, Theodoros; Weber, Justus; Rydzek, Julian; Frenz, Silke; Nerreter, Thomas; Mades, Andreas; Sadelain, Michel; Einsele, Hermann; Hudecek, Michael.
Afiliação
  • Mestermann K; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, 97080 Würzburg, Germany.
  • Giavridis T; Center for Cell Engineering and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Weber J; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, 97080 Würzburg, Germany.
  • Rydzek J; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, 97080 Würzburg, Germany.
  • Frenz S; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, 97080 Würzburg, Germany.
  • Nerreter T; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, 97080 Würzburg, Germany.
  • Mades A; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, 97080 Würzburg, Germany.
  • Sadelain M; Center for Cell Engineering and Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Einsele H; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, 97080 Würzburg, Germany.
  • Hudecek M; Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, 97080 Würzburg, Germany. hudecek_m@ukw.de.
Sci Transl Med ; 11(499)2019 07 03.
Article em En | MEDLINE | ID: mdl-31270272
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Linfócitos T / Inibidores de Proteínas Quinases / Dasatinibe Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Linfócitos T / Inibidores de Proteínas Quinases / Dasatinibe Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article