DLX5 gene regulates the Notch signaling pathway to promote glomerulosclerosis and interstitial fibrosis in uremic rats.

Wang, Xin-Fang; Zhang, Bei-Hao; Lu, Xiao-Qing; Wang, Rui-Qiang

Wang, Xin-Fang; Zhang, Bei-Hao; Lu, Xiao-Qing; Wang, Rui-Qiang.

Afiliação

Wang XF; Department of Blood Purification, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Zhang BH; Department of Blood Purification, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Lu XQ; Department of Blood Purification, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
Wang RQ; Department of Nephrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.

J Cell Physiol ; 234(12): 21825-21837, 2019 12.

Article em En | MEDLINE | ID: mdl-31297803

Assuntos

Proteínas de Homeodomínio/genética; Nefropatias/genética; Receptores Notch/metabolismo; Fatores de Transcrição/genética; Transcriptoma/genética; Animais; Genes Homeobox/genética; Rim/patologia; Nefropatias/patologia; Masculino; Ratos Wistar; Uremia/genética; Uremia/patologia

Palavras-chave

DLX5; Notch1 signaling pathway; gene silencing; glomerular sclerosis; kidney interstitial fibrosis; uremia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas de Homeodomínio / Receptores Notch / Transcriptoma / Nefropatias Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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