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Design, synthesis, biological evaluation and docking study of novel indole-2-amide as anti-inflammatory agents with dual inhibition of COX and 5-LOX.
Huang, Yuanzheng; Zhang, Bin; Li, Jiaming; Liu, Huicai; Zhang, Yanchun; Yang, Zhang; Liu, Wandong.
Afiliação
  • Huang Y; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230031, China.
  • Zhang B; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230031, China.
  • Li J; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230031, China; Department of Medicinal Chemistry, Anhui Academy of Chinese Medicine, Hefei, 230031, China. Electronic address: lijiaming2017@sina.com.
  • Liu H; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230031, China.
  • Zhang Y; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230031, China; Department of Medicinal Chemistry, Anhui Academy of Chinese Medicine, Hefei, 230031, China.
  • Yang Z; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230031, China.
  • Liu W; School of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230031, China.
Eur J Med Chem ; 180: 41-50, 2019 Oct 15.
Article em En | MEDLINE | ID: mdl-31299586
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Anti-Inflamatórios não Esteroides / Inibidores de Lipoxigenase / Inibidores de Ciclo-Oxigenase / Amidas / Indóis Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Anti-Inflamatórios não Esteroides / Inibidores de Lipoxigenase / Inibidores de Ciclo-Oxigenase / Amidas / Indóis Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article