Diagnostic yield and safety of ultrasound-guided bowel mass biopsies in children.
Pediatr Radiol
; 49(13): 1809-1815, 2019 12.
Article
em En
| MEDLINE
| ID: mdl-31302738
ABSTRACT
BACKGROUND:
Traditionally, ultrasound (US)-guided bowel mass biopsies are avoided in favour of endoscopic or surgical biopsies. However, endoscopy cannot easily reach lesions between the duodenojejunal flexure and the terminal ileum and lesions not involving the mucosa may not be accessible via an endoscopic route.OBJECTIVE:
The aim of this study was to report our technique and to assess the diagnostic accuracy and safety of US-guided biopsy of bowel masses in children. MATERIALS ANDMETHODS:
We conducted a 14-year retrospective review of US-guided bowel mass biopsies at a single paediatric hospital.RESULTS:
Twenty US-guided bowel mass biopsies were performed in 19 patients (median age 6 years and 6 months, range 22 months-17 years, median weight 22 kg, range 10.2-48.4 kg). For 14 biopsies, there was no other lesion that could potentially be biopsied. A percutaneous coaxial technique was used for 19 biopsies and a transanal non-coaxial biopsy was performed in 1. A median of 9 (range 2-15) cores of tissue was obtained at each biopsy. The technical success rate and adequacy of diagnostic yield were 100%. The most common diagnosis was lymphoma, which occurred in 16 biopsies. Three biopsies contained mucosa. There was one complication out of 20 biopsies (5%, 95% confidence interval 0-15%) a self-limiting, post biopsy pyrexia. Nineteen procedures were accompanied by a bone marrow aspirate and/or trephine within 2 weeks of the bowel biopsy, only one of which was diagnostic.CONCLUSION:
US-guided bowel mass biopsy can be performed safely in children, with a high diagnostic yield and low complication rate.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Linfoma de Células B
/
Linfoma de Burkitt
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Ultrassonografia de Intervenção
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Colo
/
Segurança do Paciente
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Biópsia Guiada por Imagem
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Região como assunto:
America do norte
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article