Disseminated Bacille Calmette-Guérin infection in a patient with severe combined immunodeficiency caused by JAK3 gene mutation.
Pediatr Dermatol
; 36(5): 672-676, 2019 Sep.
Article
em En
| MEDLINE
| ID: mdl-31309596
ABSTRACT
Bacille Calmette-Guérin (BCG), a live attenuated vaccine prepared using Mycobacterium bovis, can prevent tuberculosis in children and is routinely administered to infants in China and many other countries. A serious complication following vaccination is disseminated BCG infection. The risk is greatly increased in patients with severe combined immunodeficiency disease (SCID), a syndrome characterized by deficiency of both humoral and cellular immunity. We report a case of disseminated BCG infection in an infant with SCID caused by two novel janus kinase 3 (JAK3) gene mutations.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tuberculose
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Vacina BCG
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Adjuvantes Imunológicos
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Imunodeficiência Combinada Severa
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Janus Quinase 3
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Mutação
Limite:
Female
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Humans
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Infant
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article