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Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment.
Zemek, Rachael M; De Jong, Emma; Chin, Wee Loong; Schuster, Iona S; Fear, Vanessa S; Casey, Thomas H; Forbes, Cath; Dart, Sarah J; Leslie, Connull; Zaitouny, Ayham; Small, Michael; Boon, Louis; Forrest, Alistair R R; Muiri, Daithi O; Degli-Esposti, Mariapia A; Millward, Michael J; Nowak, Anna K; Lassmann, Timo; Bosco, Anthony; Lake, Richard A; Lesterhuis, W Joost.
Afiliação
  • Zemek RM; School of Biomedical Sciences, University of Western Australia, M503, Crawley, WA 6009, Australia.
  • De Jong E; National Centre for Asbestos Related Diseases, 5th Floor QQ Block, 6 Verdun Street, Nedlands, WA 6009, Australia.
  • Chin WL; Telethon Kids Institute, University of Western Australia, PO Box 855, West Perth, WA 6872, Australia.
  • Schuster IS; National Centre for Asbestos Related Diseases, 5th Floor QQ Block, 6 Verdun Street, Nedlands, WA 6009, Australia.
  • Fear VS; Medical School, University of Western Australia, M503, Crawley, WA 6009, Australia.
  • Casey TH; Department of Medical Oncology, Sir Charles Gairdner Hospital, Hospital Ave, Nedlands, WA 6009, Australia.
  • Forbes C; Immunology and Virology Program, Centre for Ophthalmology and Visual Science, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.
  • Dart SJ; Centre for Experimental Immunology, Lions Eye Institute, 2 Verdun Street, Nedlands, WA 6009, Australia.
  • Leslie C; Infection and Immunity Program and Department of Microbiology, Biomedicine Discovery Institute, Monash University, VIC 3800, Australia.
  • Zaitouny A; National Centre for Asbestos Related Diseases, 5th Floor QQ Block, 6 Verdun Street, Nedlands, WA 6009, Australia.
  • Small M; Medical School, University of Western Australia, M503, Crawley, WA 6009, Australia.
  • Boon L; School of Biomedical Sciences, University of Western Australia, M503, Crawley, WA 6009, Australia.
  • Forrest ARR; National Centre for Asbestos Related Diseases, 5th Floor QQ Block, 6 Verdun Street, Nedlands, WA 6009, Australia.
  • Muiri DO; National Centre for Asbestos Related Diseases, 5th Floor QQ Block, 6 Verdun Street, Nedlands, WA 6009, Australia.
  • Degli-Esposti MA; Medical School, University of Western Australia, M503, Crawley, WA 6009, Australia.
  • Millward MJ; School of Biomedical Sciences, University of Western Australia, M503, Crawley, WA 6009, Australia.
  • Nowak AK; National Centre for Asbestos Related Diseases, 5th Floor QQ Block, 6 Verdun Street, Nedlands, WA 6009, Australia.
  • Lassmann T; Department of Anatomical Pathology, PathWest Laboratory Medicine, QEII Medical Centre, Nedlands, WA 6009, Australia.
  • Bosco A; School of Mathematics and Statistics, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.
  • Lake RA; CSIRO, Mineral Resources, 26 Dick Perry Ave, Kensington, WA, 6152, Australia.
  • Lesterhuis WJ; School of Mathematics and Statistics, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.
Sci Transl Med ; 11(501)2019 07 17.
Article em En | MEDLINE | ID: mdl-31316010
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Transdução de Sinais / Fator de Transcrição STAT1 / Microambiente Tumoral / Imunoterapia Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Transdução de Sinais / Fator de Transcrição STAT1 / Microambiente Tumoral / Imunoterapia Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article