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EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells.
Chen, Yue-Hong; Lv, Hao; Shen, Ning; Wang, Xiao-Min; Tang, Shuai; Xiong, Bing; Ding, Jian; Geng, Mei-Yu; Huang, Min.
Afiliação
  • Chen YH; School of Life Science, Shanghai University, Shanghai, 200444, China.
  • Lv H; Division of Antitumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Shen N; School of Life Science, Shanghai University, Shanghai, 200444, China.
  • Wang XM; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Tang S; School of Life Science, Shanghai University, Shanghai, 200444, China.
  • Xiong B; School of Life Science, Shanghai University, Shanghai, 200444, China.
  • Ding J; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Geng MY; School of Life Science, Shanghai University, Shanghai, 200444, China.
  • Huang M; Department of Medicinal Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Acta Pharmacol Sin ; 41(2): 270-277, 2020 Feb.
Article em En | MEDLINE | ID: mdl-31316177
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas p21(ras) / Receptor EphA2 / Nucleotídeo Cíclico Fosfodiesterase do Tipo 6 / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas p21(ras) / Receptor EphA2 / Nucleotídeo Cíclico Fosfodiesterase do Tipo 6 / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article