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Ara-c induces cell cycle G1/S arrest by inducing upregulation of the INK4 family gene or directly inhibiting the formation of the cell cycle-dependent complex CDK4/cyclin D1.
Sun, Fuze; Li, Niannian; Tong, Xiaoling; Zeng, Jie; He, Songzhen; Gai, Tingting; Bai, Yanmin; Liu, Lanlan; Lu, Kunpeng; Shen, Jianghong; Han, Minjin; Lu, Cheng; Dai, Fangyin.
Afiliação
  • Sun F; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
  • Li N; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
  • Tong X; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
  • Zeng J; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
  • He S; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
  • Gai T; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
  • Bai Y; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
  • Liu L; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
  • Lu K; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
  • Shen J; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
  • Han M; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
  • Lu C; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
  • Dai F; State Key Laboratory of Silkworm Genome Biology, Key Laboratory of Sericultural Biology and Genetic Breeding, Ministry of Agriculture, College of Biotechnology, Southwest University , Chongqing , China.
Cell Cycle ; 18(18): 2293-2306, 2019 09.
Article em En | MEDLINE | ID: mdl-31322047
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Regulação para Cima / Ciclina D1 / Citarabina / Quinase 4 Dependente de Ciclina / Proteínas Inibidoras de Quinase Dependente de Ciclina / Pontos de Checagem da Fase G1 do Ciclo Celular / Pontos de Checagem da Fase S do Ciclo Celular / Neoplasias Renais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Regulação para Cima / Ciclina D1 / Citarabina / Quinase 4 Dependente de Ciclina / Proteínas Inibidoras de Quinase Dependente de Ciclina / Pontos de Checagem da Fase G1 do Ciclo Celular / Pontos de Checagem da Fase S do Ciclo Celular / Neoplasias Renais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article