Chalcone skeleton promotes transcription of gp91-phox gene but inhibits expression of gp91-phox protein, and hydroxyl groups in hydroxychalcones participate in the stable expression of gp91-phox protein.

Kikuchi, Hidehiko; Mimuro, Hitomi; Madhyastha, Harishkumar; Kuribayashi, Futoshi

Kikuchi, Hidehiko; Mimuro, Hitomi; Madhyastha, Harishkumar; Kuribayashi, Futoshi.

Afiliação

Kikuchi H; Laboratory of Biological Chemistry, Department of Food and Nutrition, Shokei University Junior College, Kumamoto, Japan.
Mimuro H; Division of Bacteriology, Department of Infectious Diseases Control, International Research Center for Infectious Diseases, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Madhyastha H; Department of Infection Microbiology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.
Kuribayashi F; Department of Applied Physiology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.

Microbiol Immunol ; 63(10): 438-443, 2019 Oct.

Article em En | MEDLINE | ID: mdl-31329291

Assuntos

Chalcona/farmacologia; Chalconas/farmacologia; NADPH Oxidase 2/genética; NADPH Oxidase 2/metabolismo; Superóxidos/metabolismo; Humanos; Tretinoína/química; Células U937

Palavras-chave

butein; chalcone; gp91-phox; superoxide

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Chalcona / Superóxidos / Chalconas / NADPH Oxidase 2 Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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