The Efficacy of Miniaturized Repetitive Transcranial Magnetic Stimulation in Patients with Depression.
Clin Psychopharmacol Neurosci
; 17(3): 409-414, 2019 Aug 31.
Article
em En
| MEDLINE
| ID: mdl-31352707
ABSTRACT
OBJECTIVE:
The present study aimed to evaluate the efficacy of repetitive transcranial magnetic stimulation (rTMS) at a high frequency using a miniaturized device compared to standard rTMS and sham rTMS for the treatment of depression.METHODS:
Fifty-four patients with depression were randomly assigned to either 15 days of miniaturized, standard, or sham rTMS. The stimulation consisted of 60 trains of 5 seconds at 10 Hz for 30 minutes. Clinical measures were assessed at baseline and on the final day of the stimulation.RESULTS:
A repeated-measures analysis of variance revealed a significant main effect of time and a time by group interaction on Hamilton Rating Scale for Depression scores. There were no significant correlations between individual motor thresholds and changes of clinical outcomes. Our results revealed a significant reduction in the Hamilton Rating Scale for Depression in the miniaturized and standard groups compared to the sham group.CONCLUSION:
The antidepressant utility of miniaturized rTMS using subthreshold stimulation was comparable to that of standard stimulation.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article