One new and seven known triterpene glycosides from the aerial parts of Cimicifuga dahurica.
J Asian Nat Prod Res
; 22(8): 788-793, 2020 Aug.
Article
em En
| MEDLINE
| ID: mdl-31357881
ABSTRACT
One new triterpene glycoside, asiaticoside I (1), along with seven known ones (2-8), were isolated from the aerial parts of Cimicifuga dahurica (Turcz.) Maxim. The structure of 1 was elucidated on the basis of extensive spectroscopic methods including 1D-NMR, 2D-NMR and MS data. The structures of known compounds were determined by comparison with the literature data. Compound 1 exhibited moderate cell growth inhibitory activities in vitro against HELF, non-small cell lung cancer A549, and pancreatic cancer PANC-1 cell lines, with IC50 values of 62.97, 43.19, and 60.40 µM, respectively.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Triterpenos
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Carcinoma Pulmonar de Células não Pequenas
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Cimicifuga
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Neoplasias Pulmonares
Limite:
Humans
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article