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Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Henes, Mina; Lockbaum, Gordon J; Kosovrasti, Klajdi; Leidner, Florian; Nachum, Gily S; Nalivaika, Ellen A; Lee, Sook-Kyung; Spielvogel, Ean; Zhou, Shuntai; Swanstrom, Ronald; Bolon, Daniel N A; Kurt Yilmaz, Nese; Schiffer, Celia A.
Afiliação
  • Henes M; Department of Biochemistry and Molecular Pharmacology , University of Massachusetts Medical School , Worcester , Massachusetts 01605 , United States.
  • Lockbaum GJ; Department of Biochemistry and Molecular Pharmacology , University of Massachusetts Medical School , Worcester , Massachusetts 01605 , United States.
  • Kosovrasti K; Department of Biochemistry and Molecular Pharmacology , University of Massachusetts Medical School , Worcester , Massachusetts 01605 , United States.
  • Leidner F; Department of Biochemistry and Molecular Pharmacology , University of Massachusetts Medical School , Worcester , Massachusetts 01605 , United States.
  • Nachum GS; Department of Biochemistry and Molecular Pharmacology , University of Massachusetts Medical School , Worcester , Massachusetts 01605 , United States.
  • Nalivaika EA; Department of Biochemistry and Molecular Pharmacology , University of Massachusetts Medical School , Worcester , Massachusetts 01605 , United States.
  • Lee SK; Department of Biochemistry and Biophysics and the UNC Center for AIDS Research , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
  • Spielvogel E; Department of Biochemistry and Biophysics and the UNC Center for AIDS Research , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
  • Zhou S; Department of Biochemistry and Biophysics and the UNC Center for AIDS Research , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
  • Swanstrom R; Department of Biochemistry and Biophysics and the UNC Center for AIDS Research , University of North Carolina at Chapel Hill , Chapel Hill , North Carolina 27599 , United States.
  • Bolon DNA; Department of Biochemistry and Molecular Pharmacology , University of Massachusetts Medical School , Worcester , Massachusetts 01605 , United States.
  • Kurt Yilmaz N; Department of Biochemistry and Molecular Pharmacology , University of Massachusetts Medical School , Worcester , Massachusetts 01605 , United States.
  • Schiffer CA; Department of Biochemistry and Molecular Pharmacology , University of Massachusetts Medical School , Worcester , Massachusetts 01605 , United States.
ACS Chem Biol ; 14(11): 2441-2452, 2019 11 15.
Article em En | MEDLINE | ID: mdl-31361460
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protease de HIV / Inibidores da Protease de HIV / Farmacorresistência Viral / Darunavir Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Protease de HIV / Inibidores da Protease de HIV / Farmacorresistência Viral / Darunavir Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article