Time-resolved FRET and NMR analyses reveal selective binding of peptides containing the LC3-interacting region to ATG8 family proteins.

Atkinson, Jennifer M; Ye, Yansheng; Gebru, Melat T; Liu, Qiang; Zhou, Shouhao; Young, Megan M; Takahashi, Yoshinori; Lin, Qing; Tian, Fang; Wang, Hong-Gang

Atkinson, Jennifer M; Ye, Yansheng; Gebru, Melat T; Liu, Qiang; Zhou, Shouhao; Young, Megan M; Takahashi, Yoshinori; Lin, Qing; Tian, Fang; Wang, Hong-Gang.

Afiliação

Atkinson JM; Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania 17033.
Ye Y; Department of Biochemistry and Molecular Biology, Penn State College of Medicine, Hershey, Pennsylvania 17033.
Gebru MT; Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania 17033.
Liu Q; Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania 17033.
Zhou S; Department of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania 17033.
Young MM; Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania 17033.
Takahashi Y; Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania 17033.
Lin Q; Department of Chemistry, State University of New York at Buffalo, Buffalo, New York 14260.
Tian F; Department of Biochemistry and Molecular Biology, Penn State College of Medicine, Hershey, Pennsylvania 17033 ftian@psu.edu.
Wang HG; Department of Pediatrics, Penn State College of Medicine, Hershey, Pennsylvania 17033 huw11@psu.edu.

J Biol Chem ; 294(38): 14033-14042, 2019 09 20.

Article em En | MEDLINE | ID: mdl-31362979

Assuntos

Família da Proteína 8 Relacionada à Autofagia/genética; Família da Proteína 8 Relacionada à Autofagia/ultraestrutura; Proteínas Associadas aos Microtúbulos/metabolismo; Motivos de Aminoácidos; Animais; Autofagia; Família da Proteína 8 Relacionada à Autofagia/metabolismo; Proteínas de Transporte/metabolismo; Transferência Ressonante de Energia de Fluorescência/métodos; Humanos; Imageamento por Ressonância Magnética; Espectroscopia de Ressonância Magnética/métodos; Proteínas Associadas aos Microtúbulos/ultraestrutura; Mitofagia; Peptídeos/metabolismo; Ligação Proteica; Domínios e Motivos de Interação entre Proteínas/fisiologia

Palavras-chave

Atg8; LC3; LIR; autophagy; fluorescence resonance energy transfer (FRET); mitophagy; nuclear magnetic resonance (NMR); peptide interaction; protein-protein interaction

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Família da Proteína 8 Relacionada à Autofagia / Proteínas Associadas aos Microtúbulos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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