Characterization of phenolic compounds from Eugenia supra-axillaris leaf extract using HPLC-PDA-MS/MS and its antioxidant, anti-inflammatory, antipyretic and pain killing activities in vivo.

Hegazi, Nesrine M; Sobeh, Mansour; Rezq, Samar; El-Raey, Mohamed A; Dmirieh, Malak; El-Shazly, Assem M; Mahmoud, Mona F; Wink, Michael

Hegazi, Nesrine M; Sobeh, Mansour; Rezq, Samar; El-Raey, Mohamed A; Dmirieh, Malak; El-Shazly, Assem M; Mahmoud, Mona F; Wink, Michael.

Afiliação

Hegazi NM; Department of Phytochemistry and Plant Systematics, Division of Pharmaceutical Industries, National Research Center, Dokki, Cairo, Egypt.
Sobeh M; Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany. sobeh@uni-heidelberg.de.
Rezq S; AgroBioSciences Research Division, Mohammed VI Polytechnic University, Lot 660-Hay Moulay Rachid, 43150, Ben-Guerir, Morocco. sobeh@uni-heidelberg.de.
El-Raey MA; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Dmirieh M; Department of Phytochemistry and Plant Systematics, Division of Pharmaceutical Industries, National Research Center, Dokki, Cairo, Egypt.
El-Shazly AM; Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany.
Mahmoud MF; Department of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Wink M; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.

Sci Rep ; 9(1): 11122, 2019 07 31.

Article em En | MEDLINE | ID: mdl-31366955

Assuntos

Analgésicos/farmacologia; Anti-Inflamatórios/farmacologia; Antioxidantes/fisiologia; Antipiréticos/farmacologia; Eugenia/química; Extratos Vegetais/farmacologia; Folhas de Planta/química; Animais; Cromatografia Líquida de Alta Pressão/métodos; Edema/tratamento farmacológico; Edema/metabolismo; Inflamação/tratamento farmacológico; Masculino; Camundongos; Estresse Oxidativo/efeitos dos fármacos; Dor/tratamento farmacológico; Dor/metabolismo; Fenóis/química; Ratos; Ratos Wistar; Espécies Reativas de Oxigênio/metabolismo; Espectrometria de Massas em Tandem/métodos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Folhas de Planta / Antipiréticos / Eugenia / Analgésicos / Anti-Inflamatórios / Antioxidantes Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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