Oxidized HDL, as a Novel Biomarker for Calcific Aortic Valve Disease, Promotes the Calcification of Aortic Valve Interstitial Cells.

Sun, Jia Teng; Chen, Yuan Yuan; Mao, Jing Yan; Wang, Yan Ping; Chen, Ya Fen; Hu, Xiang; Yang, Ke; Liu, Yan

Sun, Jia Teng; Chen, Yuan Yuan; Mao, Jing Yan; Wang, Yan Ping; Chen, Ya Fen; Hu, Xiang; Yang, Ke; Liu, Yan.

Afiliação

Sun JT; Department of Cardiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Chen YY; Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200025, People's Republic of China.
Mao JY; Institute of Cardiovascular Disease, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Road II, Shanghai, 200025, People's Republic of China.
Wang YP; Institute of Cardiovascular Disease, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Road II, Shanghai, 200025, People's Republic of China.
Chen YF; Institute of Cardiovascular Disease, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Road II, Shanghai, 200025, People's Republic of China.
Hu X; Institute of Cardiovascular Disease, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Road II, Shanghai, 200025, People's Republic of China.
Yang K; Department of Cardiac Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Liu Y; Institute of Cardiovascular Disease, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Road II, Shanghai, 200025, People's Republic of China. ykk_ykkk@126.com.

J Cardiovasc Transl Res ; 12(6): 560-568, 2019 12.

Article em En | MEDLINE | ID: mdl-31367900

Assuntos

Valva Aórtica/metabolismo; Calcinose/metabolismo; Doenças das Valvas Cardíacas/metabolismo; Lipoproteínas HDL/metabolismo; Osteoblastos/metabolismo; Osteogênese; Idoso; Fosfatase Alcalina/metabolismo; Valva Aórtica/patologia; Proteína Morfogenética Óssea 2/genética; Proteína Morfogenética Óssea 2/metabolismo; Calcinose/sangue; Calcinose/genética; Calcinose/patologia; Estudos de Casos e Controles; Células Cultivadas; Subunidade alfa 1 de Fator de Ligação ao Core/genética; Subunidade alfa 1 de Fator de Ligação ao Core/metabolismo; Estudos Transversais; Feminino; Doenças das Valvas Cardíacas/sangue; Doenças das Valvas Cardíacas/genética; Doenças das Valvas Cardíacas/patologia; Proteínas de Homeodomínio/genética; Proteínas de Homeodomínio/metabolismo; Humanos; Lipoproteínas HDL/sangue; Masculino; Pessoa de Meia-Idade; Osteoblastos/patologia; Osteogênese/genética; Oxirredução; Transdução de Sinais

Palavras-chave

Aortic valve interstitial cells; Calcific aortic valve disease; Calcification; Oxidized HDL

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoblastos / Osteogênese / Valva Aórtica / Calcinose / Doenças das Valvas Cardíacas / Lipoproteínas HDL Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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