Strain-Promoted 1,3-Dithiolium-4-olates-Alkyne Cycloaddition.
Angew Chem Int Ed Engl
; 58(41): 14544-14548, 2019 10 07.
Article
em En
| MEDLINE
| ID: mdl-31368231
ABSTRACT
Reported here is the reactivity of mesoionic 1,3-dithiolium-4-olates towards strained alkynes, leading to thiophene cycloaddition products. In the process, the potential of these dipoles towards orthogonal reaction with azides, allowing efficient double ligation reactions, was discovered. A versatile process to access benzo[c]thiophenes, in an unprecedented divergent fashion, was developed and provides a new entry to unconventional polyaromatic thiophenes.
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Coleções:
01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article