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Novel p97/VCP inhibitor induces endoplasmic reticulum stress and apoptosis in both bortezomib-sensitive and -resistant multiple myeloma cells.
Nishimura, Nao; Radwan, Mohamed O; Amano, Masayuki; Endo, Shinya; Fujii, Eri; Hayashi, Hironori; Ueno, Shikiko; Ueno, Niina; Tatetsu, Hiro; Hata, Hiroyuki; Okamoto, Yoshinari; Otsuka, Masami; Mitsuya, Hiroaki; Matsuoka, Masao; Okuno, Yutaka.
Afiliação
  • Nishimura N; Departments of Hematology, Rheumatology, and Infectious Disease, Kumamoto University Graduate School of Medicine, Kumamoto, Japan.
  • Radwan MO; Faculty of Life Sciences, Department of Bioorganic Medicinal Chemistry, Kumamoto University, Kumamoto, Japan.
  • Amano M; Chemistry of Natural Compounds Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Cairo, Egypt.
  • Endo S; Departments of Hematology, Rheumatology, and Infectious Disease, Kumamoto University Graduate School of Medicine, Kumamoto, Japan.
  • Fujii E; Departments of Hematology, Rheumatology, and Infectious Disease, Kumamoto University Graduate School of Medicine, Kumamoto, Japan.
  • Hayashi H; Faculty of Medical Sciences, Division of Informative Clinical Sciences, Kumamoto University, Kumamoto, Japan.
  • Ueno S; Departments of Hematology, Rheumatology, and Infectious Disease, Kumamoto University Graduate School of Medicine, Kumamoto, Japan.
  • Ueno N; Departments of Hematology, Rheumatology, and Infectious Disease, Kumamoto University Graduate School of Medicine, Kumamoto, Japan.
  • Tatetsu H; Departments of Hematology, Rheumatology, and Infectious Disease, Kumamoto University Graduate School of Medicine, Kumamoto, Japan.
  • Hata H; Departments of Hematology, Rheumatology, and Infectious Disease, Kumamoto University Graduate School of Medicine, Kumamoto, Japan.
  • Okamoto Y; Faculty of Medical Sciences, Division of Informative Clinical Sciences, Kumamoto University, Kumamoto, Japan.
  • Otsuka M; Faculty of Life Sciences, Department of Bioorganic Medicinal Chemistry, Kumamoto University, Kumamoto, Japan.
  • Mitsuya H; Faculty of Life Sciences, Department of Bioorganic Medicinal Chemistry, Kumamoto University, Kumamoto, Japan.
  • Matsuoka M; Departments of Hematology, Rheumatology, and Infectious Disease, Kumamoto University Graduate School of Medicine, Kumamoto, Japan.
  • Okuno Y; Departments of Hematology, Rheumatology, and Infectious Disease, Kumamoto University Graduate School of Medicine, Kumamoto, Japan.
Cancer Sci ; 110(10): 3275-3287, 2019 Oct.
Article em En | MEDLINE | ID: mdl-31368616
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Adenosina Trifosfatases / Resistencia a Medicamentos Antineoplásicos / Retículo Endoplasmático / Inibidores Enzimáticos / Bibliotecas de Moléculas Pequenas / Mieloma Múltiplo Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Adenosina Trifosfatases / Resistencia a Medicamentos Antineoplásicos / Retículo Endoplasmático / Inibidores Enzimáticos / Bibliotecas de Moléculas Pequenas / Mieloma Múltiplo Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article