Variation of Peripapillary Scleral Shape With Age.
Invest Ophthalmol Vis Sci
; 60(10): 3275-3282, 2019 08 01.
Article
em En
| MEDLINE
| ID: mdl-31369672
ABSTRACT
Purpose:
To define the shape of the anterior surface of the peripapillary sclera (PPS) and evaluate its relationship with age and ocular determinants in a population-based Chinese cohort.Methods:
The optic nerve heads of 619 healthy Chinese subjects were imaged with spectral-domain optical coherence tomography. To assess the shape of the PPS/Bruch's membrane (BM), we measured the angle between a line parallel to the nasal anterior PPS/BM boundary and one parallel to the temporal side. A negative value indicated that the PPS/BM followed an inverted v-shaped configuration (peak pointing toward the vitreous), whereas a positive value indicated that it followed a v-shaped configuration (peak pointing toward the orbital tissues). A linear regression model was used to evaluate the relationship between the PPS angle and other ocular parameters.Results:
The mean PPS angle was 3.68° ± 6.73° and the BM angle was 9.69° ± 5.05°. The PPS angle increased on average by 0.233 deg/y. A v-shaped PPS was significantly associated with age (ß = 0.087, P = 0.004), peripapillary choroidal thickness (ß = -0.479, P < 0.001), lamina cribrosa depth (ß = 0.307, P < 0.001), and BM angle (ß = 0.487, P < 0.001) after adjusting for best corrected visual acuity, central corneal thickness, and axial length.Conclusions:
The anterior surface of PPS of an elderly adult population had a v-shaped configuration and was more pronounced with increasing age, thin peripapillary choroid, and a deep cup. Such a change in shape with age could have an impact on the biomechanical environment of the optic nerve head.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Disco Óptico
/
Esclera
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Envelhecimento
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article