Resveratrol prevents palmitic-acid-induced cardiomyocyte contractile impairment.

Lieben Louis, Xavier; Raj, Pema; Meikle, Zach; Yu, Liping; Susser, Shannel E; MacInnis, Shayla; Duhamel, Todd A; Wigle, Jeffrey T; Netticadan, Thomas

Lieben Louis, Xavier; Raj, Pema; Meikle, Zach; Yu, Liping; Susser, Shannel E; MacInnis, Shayla; Duhamel, Todd A; Wigle, Jeffrey T; Netticadan, Thomas.

Afiliação

Lieben Louis X; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB R2H 2A6, Canada.
Raj P; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Meikle Z; Canadian Centre for Agri-Food Research in Health and Medicine, St. Boniface Hospital Albrechtsen, Research Centre, Winnipeg, MB R2H 2A6, Canada.
Yu L; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Susser SE; Department of Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
MacInnis S; Canadian Centre for Agri-Food Research in Health and Medicine, St. Boniface Hospital Albrechtsen, Research Centre, Winnipeg, MB R2H 2A6, Canada.
Duhamel TA; Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, MB R2H 2A6, Canada.
Wigle JT; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, MB R3E 0J9, Canada.
Netticadan T; Canadian Centre for Agri-Food Research in Health and Medicine, St. Boniface Hospital Albrechtsen, Research Centre, Winnipeg, MB R2H 2A6, Canada.

Can J Physiol Pharmacol ; 97(12): 1132-1140, 2019 Dec.

Article em En | MEDLINE | ID: mdl-31374178

Assuntos

Contração Miocárdica/efeitos dos fármacos; Miócitos Cardíacos/efeitos dos fármacos; Miócitos Cardíacos/fisiologia; Ácido Palmítico/efeitos adversos; Resveratrol/farmacologia; Animais; Apoptose/efeitos dos fármacos; Regulação da Expressão Gênica/efeitos dos fármacos; Masculino; Miócitos Cardíacos/citologia; Miócitos Cardíacos/metabolismo; Ratos; Ratos Sprague-Dawley; ATPases Transportadoras de Cálcio do Retículo Sarcoplasmático/metabolismo; Troponina I/metabolismo

Palavras-chave

acide gras saturé; cardiomyocyte contractility; contractilité des cardiomyocytes; obesity; obésité; resveratrol; resvératrol; saturated fatty acid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Palmítico / Miócitos Cardíacos / Resveratrol / Contração Miocárdica Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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