TGF-ß signaling promotes tube-structure-forming growth in pancreatic duct adenocarcinoma.

Yamaguchi, Takashi; Ikehara, Sanae; Akimoto, Yoshihiro; Nakanishi, Hayao; Kume, Masahiko; Yamamoto, Kazuo; Ohara, Osamu; Ikehara, Yuzuru

Yamaguchi, Takashi; Ikehara, Sanae; Akimoto, Yoshihiro; Nakanishi, Hayao; Kume, Masahiko; Yamamoto, Kazuo; Ohara, Osamu; Ikehara, Yuzuru.

Afiliação

Yamaguchi T; Department of Molecular and Tumor Pathology, Graduate School of Medicine, Chiba University, Chiba, 260-8670, Japan.
Ikehara S; Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, 305-8565, Japan.
Akimoto Y; Department of Molecular and Tumor Pathology, Graduate School of Medicine, Chiba University, Chiba, 260-8670, Japan.
Nakanishi H; Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, 305-8565, Japan.
Kume M; Department of Anatomy, Kyorin University School of Medicine, Mitaka, 181-8611, Japan.
Yamamoto K; Laboratory of Pathology and Clinical Research, Aichi Cancer Center Aichi Hospital, Okazaki, 444-0011, Japan.
Ohara O; Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, 277-8562, Chiba, Japan.
Ikehara Y; Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, 277-8562, Chiba, Japan.

Sci Rep ; 9(1): 11247, 2019 08 02.

Article em En | MEDLINE | ID: mdl-31375695

Assuntos

Carcinogênese/patologia; Carcinoma Ductal Pancreático/patologia; Neoplasias Pancreáticas/patologia; Esferoides Celulares/ultraestrutura; Fator de Crescimento Transformador beta1/metabolismo; Animais; Benzamidas/farmacologia; Carcinogênese/efeitos dos fármacos; Carcinoma Ductal Pancreático/genética; Técnicas de Cultura de Células; Linhagem Celular Tumoral/transplante; Dioxóis/farmacologia; Modelos Animais de Doenças; Humanos; Camundongos; Camundongos Transgênicos; Neoplasias Pancreáticas/genética; Pirazóis/farmacologia; Pirróis/farmacologia; RNA-Seq; Proteínas Recombinantes/metabolismo; Transdução de Sinais/efeitos dos fármacos; Fator de Crescimento Transformador beta1/antagonistas & inibidores

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Esferoides Celulares / Carcinoma Ductal Pancreático / Fator de Crescimento Transformador beta1 / Carcinogênese Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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