Molecular structure and transformation of the glucose dehydrogenase gene in Drosophila melanogaster.
Genetics
; 120(2): 475-84, 1988 Oct.
Article
em En
| MEDLINE
| ID: mdl-3143620
ABSTRACT
We have precisely mapped and sequenced the three 5' exons of the Drosophila melanogaster Gld gene and have identified the start sites for transcription and translation. The first exon is composed of 335 nucleotides and does not contain any putative translation start codons. The second exon is separated from the first exon by 8 kb and contains the Gld translation start codon. The inferred amino acid sequence of the amino terminus contains two unusual features three tandem repeats of serine-alanine, and a relatively high density of cysteine residues. P element-mediated transformation experiments demonstrated that a 17.5-kb genomic fragment contains the functional and regulatory components of the Gld gene.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transformação Genética
/
Desidrogenases de Carboidrato
/
Drosophila melanogaster
/
Glucose Desidrogenase
Limite:
Animals
Idioma:
En
Ano de publicação:
1988
Tipo de documento:
Article