Linking Exome Sequencing Data with Drug Response Aberrations.
Stud Health Technol Inform
; 264: 1845-1846, 2019 Aug 21.
Article
em En
| MEDLINE
| ID: mdl-31438372
ABSTRACT
Next-generation sequencing has prompted the development of numerous -omics applications. Along with experimental procedures, various computational pipelines became available to address the inherent complexities concerning the volume and quality of data. These pipelines are effective and routinely applied; however, interpreting their outcomes into actionable evidence is still poorly addressed. In this context, this work proposes a method for translating patient genomic profiles to drug response aberrations by integrating pharmacogenomic data into sequencing data analysis pipelines.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Biologia Computacional
/
Exoma
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article