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A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma.
Vashisht Gopal, Y N; Gammon, Seth; Prasad, Rishika; Knighton, Barbara; Pisaneschi, Federica; Roszik, Jason; Feng, Ningping; Johnson, Sarah; Pramanik, Snigdha; Sudderth, Jessica; Sui, Dawen; Hudgens, Courtney; Fischer, Grant M; Deng, Wanleng; Reuben, Alexandre; Peng, Weiyi; Wang, Jian; McQuade, Jennifer L; Tetzlaff, Michael T; Di Francesco, Maria E; Marszalek, Joe; Piwnica-Worms, David; DeBerardinis, Ralph J; Davies, Michael A.
Afiliação
  • Vashisht Gopal YN; Department of Melanoma Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas. vynanda@mdanderson.org.
  • Gammon S; Department of Translational Molecular Pathology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Prasad R; Department of Cancer Systems Imaging, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Knighton B; Department of Melanoma Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Pisaneschi F; Department of Melanoma Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Roszik J; Department of Cancer Systems Imaging, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Feng N; Department of Melanoma Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Johnson S; Center for Co-Clinical Trials, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Pramanik S; Center for Co-Clinical Trials, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Sudderth J; Department of Melanoma Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Sui D; Children's Medical Research Institute, University of Texas Southwestern Medical Center, Dallas, Texas.
  • Hudgens C; Department of Biostatistics, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Fischer GM; Department of Translational Molecular Pathology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Deng W; Department of Melanoma Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Reuben A; Department of Cancer Biology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Peng W; Department of Melanoma Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Wang J; Department of Thoracic H&N Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • McQuade JL; Department of Biology and Biochemistry, University of Houston, Houston, Texas.
  • Tetzlaff MT; Department of Biostatistics, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Di Francesco ME; Department of Melanoma Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Marszalek J; Department of Translational Molecular Pathology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Piwnica-Worms D; Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • DeBerardinis RJ; Institute for Applied Cancer Science, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
  • Davies MA; Center for Co-Clinical Trials, University of Texas M.D. Anderson Cancer Center, Houston, Texas.
Clin Cancer Res ; 25(21): 6429-6442, 2019 11 01.
Article em En | MEDLINE | ID: mdl-31439581
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosforilação Oxidativa / Sistema de Sinalização das MAP Quinases / Inibidores de Proteínas Quinases / Melanoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosforilação Oxidativa / Sistema de Sinalização das MAP Quinases / Inibidores de Proteínas Quinases / Melanoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article