Rats with a Human Mutation of NFU1 Develop Pulmonary Hypertension.

Niihori, Maki; Eccles, Cody A; Kurdyukov, Sergey; Zemskova, Marina; Varghese, Mathews Valuparampil; Stepanova, Anna A; Galkin, Alexander; Rafikov, Ruslan; Rafikova, Olga

Niihori, Maki; Eccles, Cody A; Kurdyukov, Sergey; Zemskova, Marina; Varghese, Mathews Valuparampil; Stepanova, Anna A; Galkin, Alexander; Rafikov, Ruslan; Rafikova, Olga.

Afiliação

Niihori M; Division of Endocrinology, Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona; and.
Eccles CA; Division of Endocrinology, Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona; and.
Kurdyukov S; Division of Endocrinology, Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona; and.
Zemskova M; Division of Endocrinology, Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona; and.
Varghese MV; Division of Endocrinology, Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona; and.
Stepanova AA; Division of Neonatology, Department of Pediatrics, Columbia University, New York, New York.
Galkin A; Division of Neonatology, Department of Pediatrics, Columbia University, New York, New York.
Rafikov R; Division of Endocrinology, Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona; and.
Rafikova O; Division of Endocrinology, Department of Medicine, University of Arizona College of Medicine, Tucson, Arizona; and.

Am J Respir Cell Mol Biol ; 62(2): 231-242, 2020 02.

Article em En | MEDLINE | ID: mdl-31461310

Assuntos

Proteínas de Transporte/genética; Hipertensão Pulmonar/genética; Hipertrofia Ventricular Direita/genética; Mutação/genética; Animais; Humanos; Hipertensão Pulmonar/metabolismo; Hipertrofia Ventricular Direita/metabolismo; Mitocôndrias/metabolismo; Proteínas Mitocondriais/genética; Proteínas Mitocondriais/metabolismo; Fenótipo; Ratos

Palavras-chave

Complex II; iron-sulfur cluster; mitochondrial dysfunction; pulmonary arterial hypertension; sex difference

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Hipertrofia Ventricular Direita / Hipertensão Pulmonar / Mutação Limite: Animals / Humans Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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