Mortality Among Men and Women in the North American Synthetic Rubber Industry, 1943 to 2009.
J Occup Environ Med
; 61(11): 887-897, 2019 11.
Article
em En
| MEDLINE
| ID: mdl-31464816
ABSTRACT
OBJECTIVE:
To evaluate 1943 to 2009 mortality among 22,785 synthetic rubber industry employees.METHODS:
Standardized mortality ratio (SMR) and internal Cox regression analyses.RESULTS:
Among hourly employees with more than or equal to 10 years worked and more than or equal to 20 years since hire, SMRs were elevated for leukemia (SMRâ=â139, 95% confidence interval [CI]â=â106 to 179), non-Hodgkin lymphoma (NHL) (SMRâ=â136, CIâ=â102 to 177), bladder cancer (SMRâ=â148, CIâ=â110 to 195) and, for women only, lung cancer (SMRâ=â225, CIâ=â103 to 427). Butadiene and styrene exposure-response trends were positive for leukemia and bladder cancer but not for NHL or for lung cancer among women.CONCLUSIONS:
Results support a causal relationship between butadiene and leukemia. Interpretation of results for lung cancer among women and for bladder cancer is uncertain because of inability to control for smoking and inadequate or inconsistent support from other studies for an association between butadiene or styrene and the latter cancers.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Borracha
/
Exposição Ocupacional
/
Indústria Manufatureira
/
Neoplasias
Tipo de estudo:
Prognostic_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
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Male
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Middle aged
País/Região como assunto:
America do norte
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article