Regulated hAAT Expression from a Novel rAAV Vector and Its Application in the Prevention of Type 1 Diabetes.

Ma, Hongxia; Lu, Yuanqing; Lowe, Keith; van der Meijden-Erkelens, Lonneke; Wasserfall, Clive; Atkinson, Mark A; Song, Sihong

Ma, Hongxia; Lu, Yuanqing; Lowe, Keith; van der Meijden-Erkelens, Lonneke; Wasserfall, Clive; Atkinson, Mark A; Song, Sihong.

Afiliação

Ma H; College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Lu Y; Department of Pharmaceutics, University of Florida, Gainesville, FL 32610, USA.
Lowe K; Department of Pharmaceutics, University of Florida, Gainesville, FL 32610, USA.
van der Meijden-Erkelens L; Department of Pharmaceutics, University of Florida, Gainesville, FL 32610, USA.
Wasserfall C; Department of Pharmaceutics, University of Florida, Gainesville, FL 32610, USA.
Atkinson MA; Department of Pathology, Immunology and Laboratory Medicine, Diabetes Institute, College of Medicine, University of Florida, Gainesville, FL 32610, USA.
Song S; Department of Pathology, Immunology and Laboratory Medicine, Diabetes Institute, College of Medicine, University of Florida, Gainesville, FL 32610, USA.

J Clin Med ; 8(9)2019 Aug 28.

Article em En | MEDLINE | ID: mdl-31466263

Palavras-chave

alpha 1 antitrypsin (AAT); autoimmune disease; gene therapy; recombinant adeno-associated virus (rAAV); serine proteinase inhibitor (SERPIN); tet-on promoter; type 1 diabetes (T1D)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2019 Tipo de documento: Article