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Position ß57 of I-Ag7 controls early anti-insulin responses in NOD mice, linking an MHC susceptibility allele to type 1 diabetes onset.
Gioia, Louis; Holt, Marie; Costanzo, Anne; Sharma, Siddhartha; Abe, Brian; Kain, Lisa; Nakayama, Maki; Wan, Xiaoxiao; Su, Andrew; Mathews, Clayton; Chen, Yi-Guang; Unanue, Emil; Teyton, Luc.
Afiliação
  • Gioia L; Department of Integrative Structural and Computational Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Holt M; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Costanzo A; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Sharma S; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Abe B; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Kain L; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Nakayama M; Department of Pediatrics and Department of Immunology and Microbiology, Barbara Davis Center for Diabetes, University of Colorado School of Medicine, Denver, CO 80045, USA.
  • Wan X; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Su A; Department of Integrative Structural and Computational Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
  • Mathews C; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
  • Chen YG; University of Florida College of Medicine, Gainesville, FL 32611, USA.
  • Unanue E; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Teyton L; Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA 92037, USA. lteyton@scripps.edu.
Sci Immunol ; 4(38)2019 08 30.
Article em En | MEDLINE | ID: mdl-31471352

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Diabetes Mellitus Tipo 1 / Alelos / Insulina / Complexo Principal de Histocompatibilidade Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Diabetes Mellitus Tipo 1 / Alelos / Insulina / Complexo Principal de Histocompatibilidade Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article