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Consensus guidance of nebulizer therapy for acute rhinosinusitis.
Ohki, Motofumi; Hyo, Yukiyoshi; Yoshiyama, Yuji; Takano, Hiroshi; Takahata, Junko; Suzuki, Motohiko; Takeno, Sachio; Ogoshi, Toshio; Suzuki, Kenji; Takeuchi, Kazuhiko; Naito, Kensei; Haruna, Shinichi; Fujisawa, Toshiyuki; Yamaguchi, Sota; Hotomi, Muneki; Kawauchi, Hideyuki; Kurono, Yuichi.
Afiliação
  • Ohki M; Department of Otorhinolaryngology, Kitasato University Medical Center, Saitama, Japan.
  • Hyo Y; Department of Otolaryngology, Kawasaki Medical School, Kurashiki, Japan. Electronic address: yuki-hyo@med.kawasaki-m.ac.jp.
  • Yoshiyama Y; Kitasato University School of Pharmacy, Kanagawa, Japan.
  • Takano H; Bio-microfluidics Science Research Center, Doshisha University, Kyoto, Japan.
  • Takahata J; Department of Otorhinolaryngology, Hirosaki University Graduate School of Medicine, Aomori, Japan.
  • Suzuki M; Department of Otorhinolaryngology, Nagoya City University, Nagoya, Japan.
  • Takeno S; Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
  • Ogoshi T; Toho Kamagaya Hospital, Chiba, Japan.
  • Suzuki K; Yonaha General Hospital, Kuwana, Mie, Japan.
  • Takeuchi K; Department of Otorhinolaryngology, Head & Neck Surgery, Mie University Graduate School of Medicine, Mie, Japan.
  • Naito K; Principal of Academy of Nursing, Fujita Health University, Toyoake, Japan.
  • Haruna S; Department of Otorhinolaryngology, Dokkyo Medical University, Tochigi, Japan.
  • Fujisawa T; Fujisawa ENT Clinic, Nagoya, Japan.
  • Yamaguchi S; Department of Otorhinolaryngology, Toho University Ohashi Medical Center, Tokyo, Japan.
  • Hotomi M; Department of Otorhinolaryngology-Head and Neck Surgery, Wakayama Medical University, Wakayama, Japan.
  • Kawauchi H; Department of Otorhinolaryngology, Shimane University Faculty of Medicine, Shimane, Japan.
  • Kurono Y; Department of Otolaryngology, Faculty of Medicine, Kagoshima University, Japan.
Auris Nasus Larynx ; 47(1): 18-24, 2020 Feb.
Article em En | MEDLINE | ID: mdl-31477344
The guidance deals with the recommended applications, procedures, and safety management of nebulizer therapy for acute rhinosinusitis. In Japan, nebulizer therapy for sinusitis has been covered by public health insurance since 1958 and has been commonly carried out nationwide. The Japan Society for Infection and Aerosol in Otorhinolaryngology and the Oto-Rhino-Laryngological Society of Japan set up a working group to draw up a consensus guidance on nebulizer therapy for acute rhinosinusitis. The device for nebulizer therapy are classified into jet, ultrasound, and mesh types. In Japan, cefmenoxime hydrochloride (CMX) was approved for use in nebulizer therapy since 1996. The widening of the obstructed lesions such as large polyps prior to nebulizer therapy were recommended. The numbers of times of nebulizer therapy is recommended for three times in a week for at least for 2 weeks (cure rate: 68%, eradication ratio: 48%). Concerns should be pay for the changes of activity of medicine due to the mixing and bacterial contamination. Pseudomonas cepacia growing in a short even in both saline and distilled water leads to contamination at high concentrations by 2 days. Nebulizer therapy is an effective treatment based on a drug delivery system (DDS) to the nasal and paranasal cavities. The therapy effectively increases the local drug concentration by promptly and uniformly delivering drugs to a targeted local site. The therapy is safe with less systemic absorption and with few adverse reactions.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinusite / Nebulizadores e Vaporizadores / Rinite / Corticosteroides / Antibacterianos Tipo de estudo: Guideline Limite: Humans País/Região como assunto: Asia Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinusite / Nebulizadores e Vaporizadores / Rinite / Corticosteroides / Antibacterianos Tipo de estudo: Guideline Limite: Humans País/Região como assunto: Asia Idioma: En Ano de publicação: 2020 Tipo de documento: Article