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Clofarabine­phytochemical combination exposures in CML cells inhibit DNA methylation machinery, upregulate tumor suppressor genes and promote caspase­dependent apoptosis.
Kaufman-Szymczyk, Agnieszka; Majda, Katarzyna; Szulawska-Mroczek, Agata; Fabianowska-Majewska, Krystyna; Lubecka, Katarzyna.
Afiliação
  • Kaufman-Szymczyk A; Department of Biomedical Chemistry, Faculty of Health Sciences, Medical University of Lodz, 92­215 Lodz, Poland.
  • Majda K; Department of Biomedical Chemistry, Faculty of Health Sciences, Medical University of Lodz, 92­215 Lodz, Poland.
  • Szulawska-Mroczek A; Department of Biomedical Chemistry, Faculty of Health Sciences, Medical University of Lodz, 92­215 Lodz, Poland.
  • Fabianowska-Majewska K; Faculty of Medicine, Lazarski University, 02­662 Warsaw, Poland.
  • Lubecka K; Department of Biomedical Chemistry, Faculty of Health Sciences, Medical University of Lodz, 92­215 Lodz, Poland.
Mol Med Rep ; 20(4): 3597-3608, 2019 Oct.
Article em En | MEDLINE | ID: mdl-31485618
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tretinoína / Leucemia Mielogênica Crônica BCR-ABL Positiva / Metilação de DNA / Resveratrol / Clofarabina / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tretinoína / Leucemia Mielogênica Crônica BCR-ABL Positiva / Metilação de DNA / Resveratrol / Clofarabina / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article