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Health-related quality of life and neurocognitive functioning with lomustine-temozolomide versus temozolomide in patients with newly diagnosed, MGMT-methylated glioblastoma (CeTeG/NOA-09): a randomised, multicentre, open-label, phase 3 trial.
Weller, Johannes; Tzaridis, Theophilos; Mack, Frederic; Steinbach, Joachim Peter; Schlegel, Uwe; Hau, Peter; Krex, Dietmar; Grauer, Oliver; Goldbrunner, Roland; Bähr, Oliver; Uhl, Martin; Seidel, Clemens; Tabatabai, Ghazaleh; Brehmer, Stefanie; Bullinger, Lars; Galldiks, Norbert; Schaub, Christina; Kebir, Sied; Stummer, Walter; Simon, Matthias; Fimmers, Rolf; Coch, Christoph; Glas, Martin; Herrlinger, Ulrich; Schäfer, Niklas.
Afiliação
  • Weller J; Division of Clinical Neurooncology, Department of Neurology and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
  • Tzaridis T; Division of Clinical Neurooncology, Department of Neurology and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
  • Mack F; Division of Clinical Neurooncology, Department of Neurology and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
  • Steinbach JP; Dr Senckenberg Institute of Neurooncology, University of Frankfurt, Frankfurt am Main, Germany.
  • Schlegel U; Department of Neurology, University Hospital Knappschaftskrankenhaus, Ruhr-Universität Bochum, Bochum, Germany.
  • Hau P; Department of Neurology and Wilhelm Sander Neurooncology Unit, University Hospital Regensburg, Regensburg, Germany.
  • Krex D; Department of Neurosurgery, University of Dresden, Dresden, Germany.
  • Grauer O; Department of Neurology, University of Münster, Münster, Germany.
  • Goldbrunner R; Department of Neurosurgery, University of Cologne, Cologne, Germany.
  • Bähr O; Dr Senckenberg Institute of Neurooncology, University of Frankfurt, Frankfurt am Main, Germany.
  • Uhl M; Department of Neurology and Wilhelm Sander Neurooncology Unit, University Hospital Regensburg, Regensburg, Germany.
  • Seidel C; Department of Radiation Oncology, University of Leipzig, Leipzig, Germany.
  • Tabatabai G; Interdisciplinary Division of Neurooncology, University of Tübingen, Tübingen, Germany.
  • Brehmer S; Department of Neurosurgery, University of Mannheim, Mannheim, Germany.
  • Bullinger L; Department of Internal Medicine, University of Ulm, Ulm, Germany.
  • Galldiks N; Department of Neurology, University of Cologne, Cologne, Germany; Institute of Neuroscience and Medicine, Forschungszentrum Juelich, Juelich, Germany.
  • Schaub C; Division of Clinical Neurooncology, Department of Neurology and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
  • Kebir S; Division of Clinical Neurooncology, Department of Neurology and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
  • Stummer W; Department of Neurosurgery, University of Münster, Münster, Germany.
  • Simon M; Department of Neurosurgery, University Hospital Bonn, Bonn, Germany.
  • Fimmers R; Institute for Medical Biometry, Informatics and Epidemiology, University Hospital Bonn, Bonn, Germany.
  • Coch C; Study Center Bonn, University Hospital Bonn, Bonn, Germany.
  • Glas M; Division of Clinical Neurooncology, Department of Neurology and West German Cancer Center, German Cancer Consortium, Partner Site Essen, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
  • Herrlinger U; Division of Clinical Neurooncology, Department of Neurology and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany. Electronic address: ulrich.herrlinger@ukbonn.de.
  • Schäfer N; Division of Clinical Neurooncology, Department of Neurology and Center of Integrated Oncology, University Hospital Bonn, Bonn, Germany.
Lancet Oncol ; 20(10): 1444-1453, 2019 10.
Article em En | MEDLINE | ID: mdl-31488360
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Neoplasias Encefálicas / Protocolos de Quimioterapia Combinada Antineoplásica / Glioblastoma / Antineoplásicos Alquilantes / Temozolomida Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Adolescent / Adult / Aged / Humans / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Neoplasias Encefálicas / Protocolos de Quimioterapia Combinada Antineoplásica / Glioblastoma / Antineoplásicos Alquilantes / Temozolomida Tipo de estudo: Clinical_trials / Diagnostic_studies / Prognostic_studies Limite: Adolescent / Adult / Aged / Humans / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article