Exposure to silver nanoparticles primes mast cells for enhanced activation through the high-affinity IgE receptor.

Alsaleh, Nasser B; Mendoza, Ryan P; Brown, Jared M

Alsaleh, Nasser B; Mendoza, Ryan P; Brown, Jared M.

Afiliação

Alsaleh NB; Colorado Center for Nanomedicine and Nanosafety, Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, The University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Mendoza RP; Colorado Center for Nanomedicine and Nanosafety, Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, The University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Brown JM; Colorado Center for Nanomedicine and Nanosafety, Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, The University of Colorado Anschutz Medical Campus, Aurora, CO, United States. Electronic address: jared.brown@cuanschutz.edu.

Toxicol Appl Pharmacol ; 382: 114746, 2019 11 01.

Article em En | MEDLINE | ID: mdl-31494149

Assuntos

Mastócitos/efeitos dos fármacos; Mastócitos/metabolismo; Nanopartículas Metálicas/toxicidade; Receptores de IgE/metabolismo; Prata/toxicidade; Animais; Sobrevivência Celular/efeitos dos fármacos; Sobrevivência Celular/fisiologia; Células Cultivadas; Mastócitos/imunologia; Camundongos; Camundongos Endogâmicos C57BL; Receptores de IgE/agonistas; Receptores de IgE/imunologia

Palavras-chave

Allergy; Degranulation; Engineered nanomaterials; Late-phase activation; Mast cell; Sensitization; Silver nanoparticles

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Prata / Receptores de IgE / Nanopartículas Metálicas / Mastócitos Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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