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A phase Ib study of a PI3Kinase inhibitor BKM120 in combination with panitumumab in patients with KRAS wild-type advanced colorectal cancer.
Goodwin, Rachel; Jonker, Derek; Chen, Eric; Kennecke, Hagen; Cabanero, Michael; Tsao, Ming-Sound; Vickers, Michael; Bohemier, Caryn; Lim, Howard; Ritter, Heather; Tu, Dongsheng; Seymour, Lesley.
Afiliação
  • Goodwin R; Ottawa Hospital Research Institute, The Ottawa Hospital Cancer Centre, University of Ottawa, Ottawa, ON, K1H 8L6, Canada. rgoodwin@toh.on.ca.
  • Jonker D; Ottawa Hospital Research Institute, The Ottawa Hospital Cancer Centre, University of Ottawa, Ottawa, ON, K1H 8L6, Canada.
  • Chen E; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
  • Kennecke H; Virginia Mason Cancer Institute, Seattle, WA, USA.
  • Cabanero M; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
  • Tsao MS; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
  • Vickers M; Ottawa Hospital Research Institute, The Ottawa Hospital Cancer Centre, University of Ottawa, Ottawa, ON, K1H 8L6, Canada.
  • Bohemier C; Ottawa Hospital Research Institute, The Ottawa Hospital Cancer Centre, University of Ottawa, Ottawa, ON, K1H 8L6, Canada.
  • Lim H; BCCA-Vancouver Centre, Vancouver, BC, Canada.
  • Ritter H; Canadian Cancer Trials Group, Queen's University, Kingston, ON, Canada.
  • Tu D; Canadian Cancer Trials Group, Queen's University, Kingston, ON, Canada.
  • Seymour L; Canadian Cancer Trials Group, Queen's University, Kingston, ON, Canada.
Invest New Drugs ; 38(4): 1077-1084, 2020 08.
Article em En | MEDLINE | ID: mdl-31506897
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Protocolos de Quimioterapia Combinada Antineoplásica / Morfolinas / Panitumumabe / Inibidores de Fosfoinositídeo-3 Quinase / Aminopiridinas / Antineoplásicos Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Protocolos de Quimioterapia Combinada Antineoplásica / Morfolinas / Panitumumabe / Inibidores de Fosfoinositídeo-3 Quinase / Aminopiridinas / Antineoplásicos Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2020 Tipo de documento: Article