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BMSC-derived leptin and IGFBP2 promote erlotinib resistance in lung adenocarcinoma cells through IGF-1R activation in hypoxic environment.
Wang, Fan; Zhang, Liyang; Sai, Buqing; Wang, Lujuan; Zhang, Xina; Zheng, Leliang; Tang, Jiuqi; Li, Guiyuan; Xiang, Juanjuan.
Afiliação
  • Wang F; NHC Key Laboratory of Carcinogenesis and the Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Zhang L; Cancer Research Institute, School of Basic Medical Science, Central South University, Changsha, Hunan, China.
  • Sai B; Department of Gastroenterology, Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Changsha, Hunan, China.
  • Wang L; Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
  • Zhang X; NHC Key Laboratory of Carcinogenesis and the Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Zheng L; Cancer Research Institute, School of Basic Medical Science, Central South University, Changsha, Hunan, China.
  • Tang J; Department of Gastroenterology, Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Changsha, Hunan, China.
  • Li G; NHC Key Laboratory of Carcinogenesis and the Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Xiang J; Cancer Research Institute, School of Basic Medical Science, Central South University, Changsha, Hunan, China.
Cancer Biol Ther ; 21(1): 61-71, 2020.
Article em En | MEDLINE | ID: mdl-31559898
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptor IGF Tipo 1 / Proteína 2 de Ligação a Fator de Crescimento Semelhante à Insulina / Resistencia a Medicamentos Antineoplásicos / Leptina / Células-Tronco Mesenquimais / Cloridrato de Erlotinib / Adenocarcinoma de Pulmão / Hipóxia Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptor IGF Tipo 1 / Proteína 2 de Ligação a Fator de Crescimento Semelhante à Insulina / Resistencia a Medicamentos Antineoplásicos / Leptina / Células-Tronco Mesenquimais / Cloridrato de Erlotinib / Adenocarcinoma de Pulmão / Hipóxia Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article