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The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies.
Angus, Lindsay; Smid, Marcel; Wilting, Saskia M; van Riet, Job; Van Hoeck, Arne; Nguyen, Luan; Nik-Zainal, Serena; Steenbruggen, Tessa G; Tjan-Heijnen, Vivianne C G; Labots, Mariette; van Riel, Johanna M G H; Bloemendal, Haiko J; Steeghs, Neeltje; Lolkema, Martijn P; Voest, Emile E; van de Werken, Harmen J G; Jager, Agnes; Cuppen, Edwin; Sleijfer, Stefan; Martens, John W M.
Afiliação
  • Angus L; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Smid M; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Wilting SM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • van Riet J; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Van Hoeck A; Cancer Computational Biology Center, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Nguyen L; Department of Urology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands.
  • Nik-Zainal S; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Steenbruggen TG; Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Tjan-Heijnen VCG; Department of Medical Genetics, The Clinical School, University of Cambridge, Cambridge, UK.
  • Labots M; Department of Medical Oncology, the Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • van Riel JMGH; Department of Medical Oncology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, The Netherlands.
  • Bloemendal HJ; Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
  • Steeghs N; Department of Internal Medicine, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.
  • Lolkema MP; Department of Medical Oncology, Meander Medical Center, Amersfoort, The Netherlands.
  • Voest EE; Center for Personalized Cancer Treatment, Rotterdam, The Netherlands.
  • van de Werken HJG; Department of Medical Oncology, the Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Jager A; Center for Personalized Cancer Treatment, Rotterdam, The Netherlands.
  • Cuppen E; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Sleijfer S; Center for Personalized Cancer Treatment, Rotterdam, The Netherlands.
  • Martens JWM; Department of Medical Oncology, the Netherlands Cancer Institute, Amsterdam, The Netherlands.
Nat Genet ; 51(10): 1450-1458, 2019 10.
Article em En | MEDLINE | ID: mdl-31570896
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Neoplasias da Mama / Biomarcadores Tumorais / Neoplasias Hepáticas / Neoplasias Pulmonares / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Neoplasias da Mama / Biomarcadores Tumorais / Neoplasias Hepáticas / Neoplasias Pulmonares / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article