Pathogenic mutations in the ALS gene CCNF cause cytoplasmic mislocalization of Cyclin F and elevated VCP ATPase activity.

Yu, Yujiao; Nakagawa, Tadashi; Morohoshi, Akane; Nakagawa, Makiko; Ishida, Noriko; Suzuki, Naoki; Aoki, Masashi; Nakayama, Keiko

Yu, Yujiao; Nakagawa, Tadashi; Morohoshi, Akane; Nakagawa, Makiko; Ishida, Noriko; Suzuki, Naoki; Aoki, Masashi; Nakayama, Keiko.

Afiliação

Yu Y; Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan.
Nakagawa T; Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan.
Morohoshi A; Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan.
Nakagawa M; Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan.
Ishida N; Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan.
Suzuki N; Department of Neurology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan.
Aoki M; Department of Neurology, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan.
Nakayama K; Division of Cell Proliferation, ART, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan.

Hum Mol Genet ; 28(20): 3486-3497, 2019 10 15.

Article em En | MEDLINE | ID: mdl-31577344

Assuntos

Esclerose Lateral Amiotrófica/genética; Ciclinas/metabolismo; Citoplasma/metabolismo; Mutação/genética; Proteínas Ligases SKP Culina F-Box/metabolismo; Proteína com Valosina/metabolismo; Adenosina Trifosfatases/genética; Adenosina Trifosfatases/metabolismo; Animais; Ciclinas/genética; Masculino; Camundongos; Ligação Proteica; Proteínas Ligases SKP Culina F-Box/genética; Ubiquitinação; Proteína com Valosina/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ciclinas / Citoplasma / Proteínas Ligases SKP Culina F-Box / Proteína com Valosina / Esclerose Lateral Amiotrófica / Mutação Limite: Animals Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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