Supplementation with selenium and coenzyme Q10 in critically ill patients.
Br J Hosp Med (Lond)
; 80(10): 589-593, 2019 Oct 02.
Article
em En
| MEDLINE
| ID: mdl-31589506
ABSTRACT
Multiple organ dysfunction and resultant mortality in critically ill patients has been linked with impaired cellular energy supply and oxidative stress. Clinical studies supplementing selenium, on the basis of its role as a key cofactor of antioxidant enzymes, have reported variable outcomes in critically ill patients. However, the synergistic interaction between selenium and coenzyme Q10, which has essential roles in cellular energy supply and as an antioxidant, has not been considered in such studies. This article reviews the link between selenium and coenzyme Q10, and the potential role of their co-supplementation in critical illness.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Selênio
/
Ubiquinona
/
Estado Terminal
/
Suplementos Nutricionais
/
Insuficiência de Múltiplos Órgãos
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article