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Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells.
Fontaine, Margaux A C; Westra, Marijke M; Bot, Ilze; Jin, Han; Franssen, Aimée J P M; Bot, Martine; de Jager, Saskia C A; Dzhagalov, Ivan; He, You-Wen; van Vlijmen, Bart J M; Gijbels, Marion J J; Reutelingsperger, Chris P; van Berkel, Theo J C; Sluimer, Judith C; Temmerman, Lieve; Biessen, Erik A L.
Afiliação
  • Fontaine MAC; Experimental Vascular Pathology Group, Department of Pathology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands.
  • Westra MM; Division of BioTherapeutics, Leiden Amsterdam Centre for Drug Research, Leiden University, Leiden, the Netherlands.
  • Bot I; Division of BioTherapeutics, Leiden Amsterdam Centre for Drug Research, Leiden University, Leiden, the Netherlands.
  • Jin H; Experimental Vascular Pathology Group, Department of Pathology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands.
  • Franssen AJPM; Experimental Vascular Pathology Group, Department of Pathology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands.
  • Bot M; Division of BioTherapeutics, Leiden Amsterdam Centre for Drug Research, Leiden University, Leiden, the Netherlands.
  • de Jager SCA; Division of BioTherapeutics, Leiden Amsterdam Centre for Drug Research, Leiden University, Leiden, the Netherlands.
  • Dzhagalov I; Laboratory for Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.
  • He YW; Institue of Microbiology and Immunology, National Yang-Ming University, Taipei, 112, Taiwan.
  • van Vlijmen BJM; Institue of Microbiology and Immunology, National Yang-Ming University, Taipei, 112, Taiwan.
  • Gijbels MJJ; Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands.
  • Reutelingsperger CP; Department of Internal Medicine, Division of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands.
  • van Berkel TJC; Experimental Vascular Pathology Group, Department of Pathology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, the Netherlands.
  • Sluimer JC; Department of Molecular Genetics, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, the Netherlands.
  • Temmerman L; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, the Netherlands.
  • Biessen EAL; Division of BioTherapeutics, Leiden Amsterdam Centre for Drug Research, Leiden University, Leiden, the Netherlands.
Sci Rep ; 9(1): 14547, 2019 10 10.
Article em En | MEDLINE | ID: mdl-31601924

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Gigantes / Apoptose / Proteína de Sequência 1 de Leucemia de Células Mieloides Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Gigantes / Apoptose / Proteína de Sequência 1 de Leucemia de Células Mieloides Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2019 Tipo de documento: Article