An Evaluation of DNA Methyltransferase 1 (DNMT1) Single Nucleotide Polymorphisms and Chemotherapy-Associated Cognitive Impairment: A Prospective, Longitudinal Study.

Chan, Alexandre; Yeo, Angie; Shwe, Maung; Tan, Chia Jie; Foo, Koon Mian; Chu, Pat; Khor, Chiea Chuen; Ho, Han Kiat

Chan, Alexandre; Yeo, Angie; Shwe, Maung; Tan, Chia Jie; Foo, Koon Mian; Chu, Pat; Khor, Chiea Chuen; Ho, Han Kiat.

Afiliação

Chan A; Department of Pharmacy, National University of Singapore, Singapore, Singapore. phaac@nus.edu.sg.
Yeo A; Department of Pharmacy, National Cancer Centre Singapore, Singapore, Singapore. phaac@nus.edu.sg.
Shwe M; Duke-N.U.S. Graduate Medical School Singapore, Singapore, Singapore. phaac@nus.edu.sg.
Tan CJ; Department of Pharmacy, National University of Singapore, Singapore, Singapore.
Foo KM; Department of Pharmacy, National University of Singapore, Singapore, Singapore.
Chu P; Department of Pharmacy, National University of Singapore, Singapore, Singapore.
Khor CC; Department of Pharmacy, K.K. Women's and Children's Hospital, Singapore, Singapore.
Ho HK; Singapore Cord Blood Bank, Singapore, Singapore.

Sci Rep ; 9(1): 14570, 2019 10 10.

Article em En | MEDLINE | ID: mdl-31601979

Assuntos

Antineoplásicos/efeitos adversos; Neoplasias da Mama/tratamento farmacológico; Transtornos Cognitivos/induzido quimicamente; DNA (Citosina-5-)-Metiltransferase 1/genética; Polimorfismo de Nucleotídeo Único; Adulto; Alelos; Metilação de DNA; Feminino; Frequência do Gene; Genótipo; Humanos; Estudos Longitudinais; Masculino; Pessoa de Meia-Idade; Estudos Prospectivos; Análise de Regressão; Análise de Sequência de DNA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Transtornos Cognitivos / Polimorfismo de Nucleotídeo Único / DNA (Citosina-5-)-Metiltransferase 1 / Antineoplásicos Tipo de estudo: Clinical_trials / Diagnostic_studies / Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2019 Tipo de documento: Article

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