Comprehensive biomarker analyses identifies <i>HER2, EGFR, MET</i> RNA expression and thymidylate synthase 5'UTR SNP as predictors of benefit from S-1 adjuvant chemotherapy in Japanese patients with stage II/III gastric cancer.

Yoshikawa, Takaki; Aoyama, Toru; Sakamaki, Kentaro; Oshima, Takasi; Lin, Joyce; Zhang, Shenli; Sapari, Nur Sabrina; Soong, Richie; Tan, Iain; Chan, Xiu Bin; Bottomley, Dan; Hewitt, Lindsay C; Arai, Tomio; Teh, Bin Tean; Epstein, David; Ogata, Takashi; Kameda, Yoichi; Miyagi, Yohei; Tsuburaya, Akira; Morita, Satoshi; Grabsch, Heike I; Tan, Patrick

Comprehensive biomarker analyses identifies HER2, EGFR, MET RNA expression and thymidylate synthase 5'UTR SNP as predictors of benefit from S-1 adjuvant chemotherapy in Japanese patients with stage II/III gastric cancer.

Yoshikawa, Takaki; Aoyama, Toru; Sakamaki, Kentaro; Oshima, Takasi; Lin, Joyce; Zhang, Shenli; Sapari, Nur Sabrina; Soong, Richie; Tan, Iain; Chan, Xiu Bin; Bottomley, Dan; Hewitt, Lindsay C; Arai, Tomio; Teh, Bin Tean; Epstein, David; Ogata, Takashi; Kameda, Yoichi; Miyagi, Yohei; Tsuburaya, Akira; Morita, Satoshi; Grabsch, Heike I; Tan, Patrick.

Afiliação

Yoshikawa T; Department of Gastric Surgery, National Cancer Center Hospital, Tokyo, Japan.
Aoyama T; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Sakamaki K; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Oshima T; Department of Biostatistics and Epidemiology, Yokohama City University, Yokohama, Japan.
Lin J; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Zhang S; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore.
Sapari NS; Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School, Singapore.
Soong R; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Tan I; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Chan XB; Department of Pathology, National University of Singapore, Singapore, Singapore.
Bottomley D; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore.
Hewitt LC; Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.
Arai T; Department of Pathology, GROW School for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, NL.
Teh BT; Department of Pathology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo, Japan.
Epstein D; Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School, Singapore.
Ogata T; Cancer and Stem Cell Biology Program, Duke-NUS Graduate Medical School, Singapore.
Kameda Y; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Miyagi Y; Department of Pathology, Kanagawa Cancer Center, Yokohama, Japan.
Tsuburaya A; Molecular Pathology and Genetics Division, Kanagawa Cancer Center Research Institute, Yokohama, Japan.
Morita S; Department of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Grabsch HI; Department of Biomedical Statistics and Bioinformatics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tan P; Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.

J Cancer ; 10(21): 5130-5138, 2019.

Article em En | MEDLINE | ID: mdl-31602266

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google