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Targeting TGFßR2-mutant tumors exposes vulnerabilities to stromal TGFß blockade in pancreatic cancer.
Huang, Huocong; Zhang, Yuqing; Gallegos, Valerie; Sorrelle, Noah; Zaid, Mohamed Medhat; Toombs, Jason; Du, Wenting; Wright, Steven; Hagopian, Moriah; Wang, Zhaoning; Hosein, Abdel Nasser; Sathe, Adwait Amod; Xing, Chao; Koay, Eugene J; Driscoll, Kyla E; Brekken, Rolf A.
Afiliação
  • Huang H; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Zhang Y; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Gallegos V; Cancer Biology Graduate Program, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Sorrelle N; Department of Biological Sciences, University of Texas at El Paso, El Paso, TX, USA.
  • Zaid MM; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Toombs J; Division of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Du W; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Wright S; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Hagopian M; Cancer Biology Graduate Program, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Wang Z; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Hosein AN; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Sathe AA; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Xing C; Division of Hematology and Oncology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Koay EJ; McDermott Center of Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Driscoll KE; McDermott Center of Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX, USA.
  • Brekken RA; Division of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
EMBO Mol Med ; 11(11): e10515, 2019 11 07.
Article em En | MEDLINE | ID: mdl-31609088

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático Limite: Humans Idioma: En Ano de publicação: 2019 Tipo de documento: Article